Nucleus Genomics vs Genomisaur
Nucleus Genomics bundles whole genome sequencing with 20+ polygenic scores and hundreds of conditions for $399 plus an annual membership. Genomisaur runs 71 polygenic risk scores against the DNA file you already have for $49 one-time. Here's how they actually compare.
At a glance
You already have 23andMe, AncestryDNA, or MyHeritage, and want clinical-grade polygenic risk scores fast and for less than $50 — no new kit, no subscription.
You do not have any DNA data yet, want true 30× whole genome sequencing you can re-analyze forever, and are fine with a ~6-week turnaround and a recurring membership.
Pricing
Public list prices. Genomisaur Family Full is $99.
| Option | Price | What it is |
|---|---|---|
| Genomisaur — Full Health Report | $49 one-time | 71 PRS + trait predictions from existing DNA data |
| Nucleus Genomics | $399 kit + $39/yr | 30× WGS + ~20 PRS + 800+ conditions + traits |
| Turnaround | ~20 minutes | ~6 weeks (lab sequencing) |
| Ongoing cost | $0 (optional $20/yr auto-update) | $39/yr membership to keep viewing reports |
Competitor prices sourced from Public list price on mynucleus.com as of 2026. Update periodically; confirm on the vendor's site before purchasing.
Feature comparison
Side-by-side on the things that actually change what the product does for you.
| Feature | Genomisaur | Nucleus Genomics | Edge |
|---|---|---|---|
| Requires a new kit? | No — bring existing DNA data | Yes — saliva kit + WGS | |
| Accepts 23andMe / AncestryDNA / MyHeritage | Yes | No — WGS only | |
| Polygenic risk scores included | 71 PRS across 14 categories | ~20 PRS at launch, growing | |
| Trait and lifestyle predictions | Yes — appearance + lifestyle | Yes | |
| Per-score source publications | Every score card links to its GWAS | Limited methodology disclosure | |
| Turnaround | ~20 minutes | ~6 weeks | |
| Recurring fees | None (optional $20/yr updates) | $39/yr membership |
What each one does well
Genomisaur
- $49 one-time vs $399 + $39/yr — no subscription treadmill
- Works with 23andMe, AncestryDNA, or MyHeritage
- 71 peer-reviewed PRS across 14 categories with per-score performance metrics
- ~20 minute turnaround instead of ~6 weeks
- Your report is yours — download PDF, delete your data, no lock-in
Nucleus Genomics
- Whole genome sequencing is included — useful if you have no DNA data yet
- Hundreds of single-gene conditions on top of PRS
- Polished consumer app with a longevity-focused frame
If you already have consumer DNA data (roughly 20 million Americans do), Genomisaur is the faster and cheaper path to polygenic risk scores — 71 of them for $49, no subscription. If you have no DNA data and specifically want WGS in the box, Nucleus Genomics is a more complete one-stop purchase at $399 + $39/yr.
Frequently asked questions
Does Nucleus accept 23andMe or AncestryDNA uploads?
No. As of 2026, Nucleus Genomics only works with their own WGS data or compatible VCF uploads. If your existing data is a 23andMe or AncestryDNA genotype file, Genomisaur is the direct path to a PRS report from it.
How much does Nucleus Genomics actually cost over time?
$399 for the kit plus $39 per year to keep viewing and re-running reports. Over 3 years that is 477 USD. Genomisaur's Full Health Report is $49 one-time; optional auto-update subscription is $20/yr.
Does Genomisaur replace whole genome sequencing?
No. WGS resolves rare variants and structural changes that consumer SNP arrays cannot. Genomisaur is designed for high-utility polygenic risk + trait analysis from whatever genotype data you have.
Is any of this a replacement for medical advice?
No. Both Nucleus and Genomisaur deliver informational consumer reports and should be discussed with a qualified healthcare provider before making medical decisions.
Informational, not diagnostic
Consumer preconception reports — ours, Nucleus Genomics's, and others — are informational. Carrier and polygenic risk results should be discussed with a qualified healthcare provider or genetic counselor before making medical or reproductive decisions.