How to Read Your Polygenic Risk Score Report
You just got your Genomisaur health report. It's a lot — charts, percentiles, risk scores. Here's what each section is showing you.
The Risk Score Card
Each condition in your report gets its own card. At the center is your polygenic risk score (PRS) — a single number that summarizes your genetic predisposition to that condition. The score is calculated by combining the effects of thousands of genetic variants, each contributing a small amount of risk.
Your raw score is then compared to a reference population to produce a percentile ranking. If you're in the 75th percentile for type 2 diabetes, your genetic predisposition is higher than 75% of the reference group. The percentile is what matters most; it puts your score in context.
The Risk Spectrum
Below your percentile, a horizontal bar shows where you fall on the risk spectrum. The spectrum runs from low risk (left) to high risk (right), with your position marked. Most people cluster in the middle. Being in the top or bottom 10% is less common and more informative, so those are the scores worth paying closest attention to.
Health Categories
Your report organizes scores into 14 health categories: cardiovascular, cancer, metabolic, immune, neurological, respiratory, musculoskeletal, digestive, blood, eye health, body composition, mental health, appearance, and lifestyle traits. Within each category, conditions are sorted by clinical relevance and the strength of the underlying genetic research.
Trait Predictions
Alongside the health risk scores, your report includes trait predictions — caffeine metabolism, lactose tolerance, facial aging tendency, and similar. They use the same PRS methodology applied to non-disease traits. Some are interesting, some are surprising, and a few translate into practical lifestyle changes.
What to Do With Your Results
Your report is not a diagnosis. It's a map of your genetic predispositions. A few things to keep in mind when reading it:
Scores in the top or bottom 10% are the most actionable. A very high cardiovascular score, for example, might be a reason to prioritize heart-healthy habits or talk to your doctor about earlier screening.
Genetics is one factor among many. Family history, lifestyle, diet, exercise, and environment all play big roles. A high genetic score combined with a strong family history is more meaningful than either on its own.
The report is a useful conversation starter with your doctor, especially for conditions where early screening or prevention strategies exist.
A 99th percentile score still does not mean you will develop the condition. Most people in the top percentile for any given disease never get it. PRS tells you about predisposition, and predisposition is only part of the picture.
Downloading Your Report
You can view your report online from your Genomisaur dashboard or download it as a PDF to share with your healthcare provider. Both formats contain the same information.